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M9460714.TXT
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1994-06-25
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Document 0714
DOCN M9460714
TI The identity of Pneumocystis carinii: not a single protozoan, but a
diverse group of exotic fungi.
DT 9408
AU Stringer JR; Department of Molecular Genetics, Biochemistry, and
Microbiology,; College of Medicine, University of Cincinnati, OH
45267-0524.
SO Infect Agents Dis. 1993 Jun;2(3):109-17. Unique Identifier : AIDSLINE
MED/94228117
AB Pneumocystosis is an AIDS-associated pneumonia that is characterized by
the accumulation of very large numbers of a eucaryotic single-celled
organism called Pneumocystis carinii, which has not been cultured.
Pneumocystosis also occurs in many other mammalian species, and the
rubric P. carinii is currently used to refer to organisms associated
with this disease in all host species. This article reviews molecular
genetic data establishing that P. carinii is a fungus, that P. carinii
in people is not the same organism as P. carinii in rats, and that there
may be more than one species of P. carinii, capable of infecting an
individual patient. The implications of such genetic diversity for
understanding and combating pneumocystosis are discussed.
DE Animal Human Nomenclature Pneumocystis
carinii/*CLASSIFICATION/GENETICS Rats/MICROBIOLOGY Support, U.S.
Gov't, P.H.S. JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).